Thrombus is a biological material that can be considered as a multilayered, porous and inhomogeneous structure showing permeability gradients. Its role in the unfavorable or favorable evolution of vascular pathology has long been a matter of controversy. Its mechanical characteristics, and the hemodynamic mechanisms involved in its formation and evolution are all parameters that may play a part in the role of the thrombus as a predictive marker of the evolution of pathologies. Its characterization is essential to better understand its role/influence and to propose ad hoc models in in silico simulations.

• Topic supervised by Gautier VERHILE (IRPHE) & Fabien CANDELIER (IUSTI)

Particle clustering is a key parameter to model aggregation in turbulent flows. For heavy spherical particles, it has been shown that this phenomenon is mainly due to centrifugal forces which expel particles form high vortical regions. For thin flexible particles, the situation seems more complex. Their deformability allows the particle to wrap around the vortex core to follow the streamline. This shape is related to a difference of pressure from each side of the particles, the pressure being higher farther from the vortex core. This pressure difference is responsible of a net force that pushes the particle toward the vortex core. The balance of this net force and the centrifugal force might be at the origin of a new equilibrium distance from the vortex core (...)

• Topic supervised by Lounès TADRIST (IUSTI), Irina MARTIN (IUSTI) & Maxime CHINAUD (IUSTI)

Energy conversion systems and faculties generally involve heat. To ensure proper operation of these systems, the heat generated must be controlled by creating appropriate fluidic architectures. Numerous techniques have been implemented to ensure heat transfer at the interface between a wall and a fluid (...)

• Topic supervised by Patrice LE GAL (IRPHE), Benjamin FAVIER (IRPHE), Stephane VIAZZO (M2P2) & Uwe HARLANDER (BTU)

In the various examples mentioned above, which are particularly relevant to understanding the transition to turbulence in stratified geophysical flows, instabilities arise through the resonance of internal waves propagating in the sheared fluid [2,3,4]. In the case of Poiseuille flow, it is the Tollmien-Schlichting waves interacting with gravity waves that give rise to the instability. For strato-rotational instability, it's an interaction of gravito-inertial waves trapped at the walls, while baroclinic instability can be interpreted as the resonance of Rossby waves propagating on vertically separated layers (...)

• Topic supervised by Christophe ALMARCHA (IRPHE) & Pierre BOIVIN (M2P2)

The scientific consensus on the necessity to reduce the greenhouse gases, like carbon dioxide (CO2),tends to ban the use of carbon-based fossil energy. This leads to intense research on alternative sources of energy. One of the most promising is hydrogen, but it rises questions in terms of safety and control that need to be clarified in order to use it in domestic, transportation and industrial processes (...)fluids The scientific consensus on the necessity to reduce the greenhouse gases, like carbon dioxide (CO2),tends to ban the use of carbon-based fossil energy. This leads to intense research on alternative sources of energy. One of the most promising is hydrogen, but it rises questions in terms of safety and control that need to be clarified in order to use it in domestic, transportation and industrial processes (...)

Developing experimental technique to measure the microstructure of opaque concentrated suspensions of particles is essential to progress in the understanding of their rheology. The objectives of our project are (1) to develop a novel ultrasound tool to measure the microstructure of concentrated suspensions, and (2) establish the rheology-microstructure relationship in suspensions of red blood cells by using this ultrasound tool and dedicated numerical simulations.

This project addsreses the transport and mixing of fluid and inertial particles in a Taylor-Couette cell with permeable cylinders. Analytical expressions for the velocity and pressure fields of laminar and vortical flows have previously been obtained in this configuration and we aim at using them to compute the advection of particles in order to get new insight into their inhomogeneous and unsteady transport. To do so, some open questions such as the forces acting on a particle in the vicinity of a permeable wall must be addressed.

Crystallization is one of the main processes used in industry to produce, purify or separate solid compounds or products. The research project is to develop a continuous crystallization process allowing to produce a compound or a product With fixed properties by membrane contactor. The objective of the specific IMI project also includes the development of a technique to characterize the created crystals by X-ray microtomography and 3D image analyze.

This study aims to propose the description of possible mechanisms induced by the interaction of a shock wave impinging a cell membrane. More precisely, we attempt to estimate the shear stress on the membrane assuming that the Richtmyer-Meshkov instability drives a vorticity generation at the cell interface. Thus, we develop an original experimental approach based on highspeed microscopy phase contrast to characterize the interaction of shock wave induced by laser breakdown on vesicles or biological cells using.

• Supervised by Joel MARTHELOT (IUSTI), Cédric BELLIS & Stéphane BOURGEOIS (LMA)

Elastic sheets with mesoscale architecture obtained by folding or cutting have recently drawn considerable interest in the mechanics and engineering community. The cuts and features can be tailored to allow the sheets to morph into complex three dimensional shapes with unusual mechanical characteristics such as auxeticity, deployability and programmable non-linear properties.The main objective of the project is twofold: to identify and build a fundamental understanding of the mechanical response of hyperelastic membranes with architected cut patterns on the one hand and to transfer the resulting tunable mechanisms to prototypes for more reliable compliant medical devices on the other hand (...)